NCT03160001

Niclosamide With Etanercept in Rheumatoid Arthritis

Adjuvant Use of Niclosamide With Etanercept in Rheumatoid Arthritis: Experimental and Clinical Study

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Faiq Gorial · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Assessment of the adjuvant use Niclosamide With Etanercept in Rheumatoid Arthritis

Detailed description

In this randomized double blind placebo-controlled pilot study (Phase I study) we will assess the efficacy and safety of adjuvant use Niclosamide With Etanercept in Rheumatoid Arthritis.

Conditions

• Rheumatoid Arthritis (RA)

Interventions

Type	Name	Description
DRUG	Placebo	Patients with active RA and receive Etanercept for 8 weeks.: Placebo lactose 500mg cap twice daily
DRUG	Niclosamide	Patients with active RA and receive etanercept with niclosamide cap 500mg twice daily orally as adjuvant therapy for 8 weeks
DRUG	Etanercept	Etanercept 50mg weekly

Timeline

• Start date: 2017-08-15
• Primary completion: 2018-08-15
• Completion: 2018-12-10
• First posted: 2017-05-19
• Last updated: 2018-12-12

Locations

1 site across 1 country: Iraq

Regulatory

• FDA-regulated drug study