NCT03156322

Different Epidural Initiation Volumes

Effects of Different Epidural Initiation Volumes on Postoperative Analgesia in Cesarean Delivery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 81 (actual)
• Sponsor: Inonu University · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare the effect of different epidural initiation volumes on postoperative pain scores, local anesthetic requirements, and motor block in patients who undergo patient controlled epidural analgesia for postoperative pain after cesarean section.

Detailed description

90 minutes after combined epidural spinal catheter insertion, three different volumes (5 mL, 10 mL, and 20 mL) are administered with a patient-controlled epidural analgesia (PCEA) device through the epidural catheter. For each group, 0.625% bupivacain + 2 μg/mL fentanyl, is administered. The visual analog scale, first analgesic demand time, the number of PCEA requirement per hour, morphine requirement, nausea-vomiting, itching, motor block, hypotension, and total consumed analgesic, and ephedrine amounts of the patients are recorded in the recovery room and at postoperative 2, 4, 6, 12 hours.

Conditions

• Pain, Postoperative

Interventions

Type	Name	Description
DRUG	5 mL epidural initiation volume (bupivacaine + fentanyl)	5 mL 0.625% bupivacaine + 2 μg/mL fentanyl solution is administered from epidural catheter
DRUG	10 mL epidural initiation volume (bupivacaine + fentanyl)	10 mL 0.625% bupivacaine + 2 μg/mL fentanyl solution is administered from epidural catheter
DRUG	20 mL epidural initiation volume (bupivacaine + fentanyl)	20 mL 0.625% bupivacaine + + 2 μg/mL fentanyl solution is administered from epidural catheter

Timeline

• Start date: 2016-01-01
• Primary completion: 2016-12-01
• Completion: 2017-01-01
• First posted: 2017-05-17
• Last updated: 2017-05-18

Locations

1 site across 1 country: Turkey (Türkiye)