NCT03155139

Primary Aldosteronism In Hypertensive Patients in China

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,500 (actual)
• Sponsor: Qifu Li · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To investigate the prevalence of primary aldosteronism (PA) in Chinese patients with newly diagnosed hypertension.

Detailed description

This is a nationwide sampling study. To investigate the prevalence of primary aldosteronism (PA) in Chinese patients with hypertension, we will conduct a case detection of PA in Chinese hypertensive patients from 10 centers of China (including Beijing, Chongqing, Shanghai, Guangzhou, et al.); furthermore, a case confirmation of PA (captopril challenge test and saline infusion test) will be performed if the result of case detection is positive. This study will be completed in two years.

Conditions

• Hyperaldosteronism; Primary
• Hypertension Secondary

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Aldosterone/renin ratio (ARR) testing	Plasma aldosterone concentration tests, Direct renin concentration tests
DIAGNOSTIC_TEST	Confirmatory tests	Captopril challenge test, Saline infusion test

Timeline

• Start date: 2017-06-03
• Primary completion: 2018-11-30
• Completion: 2018-11-30
• First posted: 2017-05-16
• Last updated: 2020-10-23

Locations

1 site across 1 country: China