Trials / Completed
CompletedNCT03153436
The Effect of In-vitro Myoinositol Supplementation of Human Sperm on the Outcome of Cryopreservation
- Status
- Completed
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 41 (actual)
- Sponsor
- Sohag University · Academic / Other
- Sex
- Male
- Age
- 20 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
The objective of this study is to evaluate the effect of in-vitro myoinositol supplementation of human sperm on the outcome of cryopreservation.
Detailed description
Sperm cryopreservation is considered the most valuable and used way to preserve male reproductive function. Unfortunately, osmotic effects of freezing and thawing during the cryopreservation process negatively affect sperm morphology and motility . Myoinositol is the most biologically important form of inositol in nature. In male reproductive system, myoinositol appears to regulate sperm motility, capacitation and acrosomal reaction. The objective of this study is to evaluate the effect of in-vitro myoinositol supplementation of human sperm on the outcome of cryopreservation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Myoinositol |
Timeline
- Start date
- 2016-08-28
- Primary completion
- 2017-04-26
- Completion
- 2017-04-26
- First posted
- 2017-05-15
- Last updated
- 2017-05-16
Source: ClinicalTrials.gov record NCT03153436. Inclusion in this directory is not an endorsement.