Trials / Completed
CompletedNCT03152734
Periinterventional Outcome Study in the Elderly
Periinterventional Outcome Study in the Elderly (POSE): European, Multi-centre, Prospective Observational Cohort Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 9,500 (actual)
- Sponsor
- Mark Coburn · Academic / Other
- Sex
- All
- Age
- 80 Years
- Healthy volunteers
- Not accepted
Summary
The POSE study will predict critical stages and outcome in a large sample of all surgical and non-surgical interventional patients ≥80 years of age in Europe.
Detailed description
Elderly population (≥80 years) will increase from 5.3% of the total population in 2015 to 9% in 2040. This implies an increasing number and variety of surgical and non-surgical interventional procedures. Little is known about the in-hospital mortality rates in the overall elderly interventional population. Compared with younger interventional patients, the elderly are at greater risk of peri-interventional mortality and morbidity, because of decline in physiological and cognitive reserve, and frequent comorbidities. Previous data are mostly limited to specific populations, like the elderly hip fracture patient. The investigators aim to recruit as many as possible centers throughout Europe, to participate in this study. A total sample size of 7500 patients will provide reasonable and valid results for the study aims. The primary endpoint will be analysed by fitting a COX-Regression model to the data of the post-interventional mortality until day 30.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Surgical or non-surgical intervention | Each kind of surgical or non-surgical intervention with anesthesia applied by an anesthetist |
Timeline
- Start date
- 2017-10-01
- Primary completion
- 2019-01-30
- Completion
- 2019-01-30
- First posted
- 2017-05-15
- Last updated
- 2019-11-20
Locations
177 sites across 20 countries: Austria, Belgium, Denmark, France, Georgia, Germany, Greece, Ireland, Israel, Netherlands, North Macedonia, Poland, Portugal, Romania, Russia, Serbia, Spain, Switzerland, Turkey (Türkiye), Ukraine
Source: ClinicalTrials.gov record NCT03152734. Inclusion in this directory is not an endorsement.