NCT03148717

Preoperative vs. Postoperative Rectal Misoprostol in Cesarean Section

Preoperative vs. Postoperative Rectal Misoprostol in Cesarean Section: A Randomized, Double Blind Clinical Trial

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 300 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

This prospective double-blind placebo-controlled randomized clinical trial will be conducted at Ain-Shams University Maternity Hospital from April 2017 till December 2017. Group 1 women, candidates for cesarean section, will receive preoperative rectal 400 microgram of misoprostol, and Group 2 women will receive postoperative rectal 400 microgram of misoprostol. 2017\. 120 women candidate foe elective cesarean section will receive preoperative sublingual 400 microgram of misoprostol, and another 120 women will receive postoperative sublingual 400 microgram of misoprostol.

Conditions

• Neonatal Outcome

Interventions

Type	Name	Description
DRUG	Misoprostol	Cytotec
OTHER	Placebo	Placebo tablet similar in shape, odour and consistency to misoprostol tablet.

Timeline

• Start date: 2017-05-10
• Primary completion: 2018-03-02
• Completion: 2018-03-20
• First posted: 2017-05-11
• Last updated: 2018-03-22

Locations

1 site across 1 country: Egypt