NCT03146793

The Early Administration of Sodium Thiosulfate Should Help to Reduce the Mortality of Dialysis Patients With Calciphylaxis, From a National Cohort

National Follow-up of Dialysis Patients With Sodium Thiosufate-treated Calciphylaxis Under Temporary Use Authorization

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 600 (estimated)
• Sponsor: Centre Hospitalier St Esprit · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The national drug safety agency authorizes nominatively the use of sodium thiosulfate in dialysis patients with calciphylaxis. To date, it is the largest global cohort (more 600 patients from 2012 to 2016). We wanted to study retrospectively the fate of these patients at 6 months including mortality. Early use improves effectiveness.

Conditions

• Calciphylaxis
• Renal Insufficiency, Chronic

Interventions

Type	Name	Description
DRUG	Sodium Thiosulfate	25g intravenously 3 times per week

Timeline

• Start date: 2017-05-01
• Primary completion: 2017-12-31
• Completion: 2018-02-28
• First posted: 2017-05-10
• Last updated: 2017-05-10

Locations

1 site across 1 country: France