NCT03146455

Thromboelastography Normal Reference Values in China Hunan Province

Establishment for Thromboelastography Normal Reference Values of Healthy Adults in China Hunan Province: A Multicenter Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 498 (actual)
• Sponsor: The Third Xiangya Hospital of Central South University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study was to establish the normal reference range of Thrombelastogram parameters in Hunan by a multicenter study, and to analyze the specificity of Thrombelastogram detection and the influence of gender, age and blood type on Thrombelastogram. The study will provide basic data and statistical basis for the establishment of normal reference range of Thrombelastogram in Hunan.

Detailed description

Thrombelastograghy (TEG) is an important test to assess the blood coagulation function to monitor the whole process of perioperative coagulation. TEG can evaluate the coagulation cascade, from platelet aggregation, clot strengthening and fibrin cross-linking to eventually clot lysis in small volume of whole blood. The reference range is one important element to influence the TEG results. At present, a number of studies have shown that reference range of TEG exists significant differences between different racial and geographic. At the same time, reagent manufacturers also suggested that each TEG laboratory should establish its own reference range. So it is important to establish our own reference range of TEG to guide the clinical blood transfusion and treatment.

Conditions

• Coagulopathy
• Blood Transfusion Complication

Interventions

Type	Name	Description
OTHER	no intervention	no intervention

Timeline

• Start date: 2017-06-05
• Primary completion: 2018-01-01
• Completion: 2018-03-10
• First posted: 2017-05-10
• Last updated: 2018-03-27

Locations

1 site across 1 country: China