Clinical Trials Directory

Trials / Completed

CompletedNCT03145259

Evaluation of Bioavailability of Diclofenac Dermal Products

Status
Completed
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
12 (actual)
Sponsor
University of Maryland, Baltimore · Academic / Other
Sex
All
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

The study will utilize already FDA-approved marketed diclofenac products in healthy adults to generate data for establishing rate of drug delivery comparisons between diclofenac epolamine patches and diclofenac sodium solution in healthy adults and to determine skin concentrations.

Detailed description

The study will utilize already FDA-approved marketed diclofenac products in healthy adults to generate data for establishing rate of drug delivery comparisons between diclofenac epolamine patches and diclofenac sodium solution in healthy adults and to determine skin concentrations. This study supports FDA's continuing effort to identify the most accurate, sensitive, reproducible and efficient methods to evaluate topical dermatological drug products.

Conditions

Interventions

TypeNameDescription
DRUGDiclofenac Epolamine Patchpatch
DRUGdiclofenac sodium solutionsolution

Timeline

Start date
2017-04-19
Primary completion
2019-08-29
Completion
2020-05-15
First posted
2017-05-09
Last updated
2020-06-30
Results posted
2020-06-16

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03145259. Inclusion in this directory is not an endorsement.