NCT03141749

Venous Thromboembolism in DM1

Incidence and Predictors of Venous Thromboembolism in Myotonic Dystrophy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 2,810 (actual)
• Sponsor: Institut de Myologie, France · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The risk for venous thromboembolism (VTE) in DM1 and in other inherited myopathies, which can lead to chronic immobilization, are unknown. The purpose of this study is to evaluate incidence of VTE in cohort of patients presenting with DM1 with a comparison to a group of other inheritable myopathies and to a community-based population.

Detailed description

A cohort of more that 2,800 adult patients admitted to our Institutions between January 2000 and November 2014 with genetically proven myopathy will be retrospectively included. Any information relative to their demographic and genetic characteristics, their muscular functional status and the occurrence of VTE will be collected. Statistical analysis will be performed to estimate the incidence of venous thromboembolism in this population, to identify predictors of VTE, and to compare its incidence to a community-based population.

Conditions

• Venous Thromboembolism
• Pulmonary Embolism
• Deep Vein Thrombosis
• Myopathy
• Myotonic Dystrophy 1

Timeline

• Start date: 2000-01-01
• Primary completion: 2014-11-01
• Completion: 2017-01-01
• First posted: 2017-05-05
• Last updated: 2017-05-09