Clinical Trials Directory

Trials / Completed

CompletedNCT03141450

Plasma Concentrations of Prophylactic Cefazolin in Pediatric Patients Undergoing Cardiac Surgery With CPB

Plasma Concentrations of Prophylactic Cefazolin in Pediatric Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass

Status
Completed
Phase
Study type
Observational
Enrollment
18 (actual)
Sponsor
Mahidol University · Academic / Other
Sex
All
Age
7 Years
Healthy volunteers
Not accepted

Summary

Surgical site infection (SSI) is a serious operative complication that may be associated with any surgical procedures. It increases morbidity and mortality after cardiac surgery. Plasma concentration of prophylactic antibiotic, routinely cefazolin, is altered by effects of cardiopulmonary bypass. This study is conducted to measure the plasma concentrations of cefazolin to determine its adequacy in pediatric patients undergoing elective cardiac surgery with cardiopulmonary bypass including its correlation with the incidence of postoperative SSI.

Conditions

Timeline

Start date
2016-05-01
Primary completion
2018-01-01
Completion
2018-01-01
First posted
2017-05-05
Last updated
2020-04-06

Locations

1 site across 1 country: Thailand

Source: ClinicalTrials.gov record NCT03141450. Inclusion in this directory is not an endorsement.