NCT03140956

Pharmacokinetic of Levodopa Study in Healthy Males

Pharmacokinetics of Levodopa After Repeated Doses of Different Pellet Formulations; An Open, Randomized Study With Crossover Design in Healthy Male Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Orion Corporation, Orion Pharma · Industry
• Sex: Male
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of the study is to investigate PK of levodopa in plasma after repeated doses of 3 levodopa formulations given in combination with carbidopa and ODM-104 and compared to the PK of standard IR and CR levodopa formulations in the same combination.

Conditions

• Parkinson Disease

Interventions

Type	Name	Description
DRUG	Levodopa, carbidopa, ODM-104	Crossover design. Study treatments will be administered in randomized order 4 times a day.

Timeline

• Start date: 2017-04-19
• Primary completion: 2017-07-03
• Completion: 2017-08-03
• First posted: 2017-05-04
• Last updated: 2017-09-26

Locations

1 site across 1 country: Finland