NCT03140748

Kinetics of Serum β-D-glucan During Peritonitis With Candida in Resuscitation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Centre Hospitalier Universitaire, Amiens · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Intraabdominal fungal infections with Candida are constantly increasing. Their diagnosis and treatment is difficult. Morbidity and mortality are high. Β-D-Glucan has been proposed as a marker of systemic fungal infection in candidemia. Moreover, its kinetics is associated with therapeutic success. On the other hand, there are no data on intraabdominal infections that are much more frequent. The objective of the study is to evaluate the initial levels of β-D-glucan and its daily kinetics during the treatment of fungal peritonitis in resuscitation compared to a control group with a yeast-free peritonitis.

Conditions

• Peritonitis Infectious
• Candida Infection

Interventions

Type	Name	Description
OTHER	To evaluate the initial levels and kinetics of serum β-D-glucan	To evaluate the initial levels and kinetics of serum β-D-glucan during fungal peritonitis compared to a control group of yeast-free peritonitis

Timeline

• Start date: 2018-05-01
• Primary completion: 2021-08-22
• Completion: 2023-06-01
• First posted: 2017-05-04
• Last updated: 2025-09-19

Locations

1 site across 1 country: France