NCT03140592

Pancreatic Cancer Models Developed From EUS Guided Biopsy Tissue

EUS-guided Biopsy of Pancreatic Mass Lesions for Developing Patient -Derived Cancer Models

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 300 (estimated)
• Sponsor: Stony Brook University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Pancreatic cancer is a very aggressive cancer. Over the past 40 years there has not been much progress made in reducing deaths from this cancer. Recently, new models of pancreatic cancers have been generated from mouse and human tissues. These models have used larger pieces of tissues taken from surgical removal of pancreatic cancers. The purpose of this study is to determine whether these new pancreatic cancer models can be generated from the small biopsies we take to make the diagnosis of the pancreatic mass.

Detailed description

The Endoscopic Ultrasound guided pancreatic biopsy tissue collected for only research purposes will be used to generate organoids in a in-vivo and in-vitro setting. The development of these methods may help scientists identify new treatments for pancreatic cancer and to potentially develop more personalized approaches to treating pancreatic cancer.

Conditions

• Pancreatic Cancer
• Pancreatic Adenocarcinoma
• Pancreatic Cyst

Interventions

Type	Name	Description
PROCEDURE	Biopsy	Two extra EUS guided pancreatic biopsies collected for only research purposes.

Timeline

• Start date: 2015-01-14
• Primary completion: 2023-01-01
• Completion: 2023-01-01
• First posted: 2017-05-04
• Last updated: 2021-03-19

Locations

1 site across 1 country: United States