Trials / Completed
CompletedNCT03140085
Bacteriophages for Treating Urinary Tract Infections in Patients Undergoing Transurethral Resection of the Prostate
Bacteriophages for Treating Urinary Tract Infections in Patients Undergoing Transurethral Resection of the Prostate: A Randomized, Placebo-controlled, Double-blind Clinical Trial
- Status
- Completed
- Phase
- Phase 2 / Phase 3
- Study type
- Interventional
- Enrollment
- 97 (actual)
- Sponsor
- Balgrist University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Urinary tract infections are among the most prevalent microbial diseases and their financial burden on society is substantial. The use of bacteriophages against bacterial pathogens has gained over the last years a renewed interest, because of the continuing increase in antibiotic resistance worldwide. Thus, the aim of this study is to investigate the efficacy of intravesical bacteriophage treatment to normalize urine culture compared to intravesical placebo or standard antibiotic treatment in a randomized controlled trial following a pilot phase.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | PYO Phage | Intravescial instillation |
| DRUG | Antibiotics | Oral application |
| OTHER | Sterile bacteriology media | Sterile bacteriology media, with identical color as bacteriophage preparation |
Timeline
- Start date
- 2017-06-02
- Primary completion
- 2018-12-14
- Completion
- 2018-12-14
- First posted
- 2017-05-04
- Last updated
- 2019-03-21
Locations
1 site across 1 country: Georgia
Source: ClinicalTrials.gov record NCT03140085. Inclusion in this directory is not an endorsement.