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Active Not RecruitingNCT03139305

Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
AdventHealth Translational Research Institute · Academic / Other
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

The main purpose of this study is to examine the effect of prolonged (72 hour) administration of glucagon compared to placebo on energy expenditure in healthy, non-diabetic, obese subjects.

Conditions

Interventions

TypeNameDescription
DRUGGlucagonLow dose intravenous infusion for 72 hours at 12.5 ng/kg/min
DRUGGlucagonHigh dose intravenous infusion for 72 hours at 25 ng/kg/min
DRUGPlaceboIntravenous infusion of saline for 72 hours

Timeline

Start date
2017-10-24
Primary completion
2018-02-14
Completion
2027-02-01
First posted
2017-05-03
Last updated
2026-03-30

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03139305. Inclusion in this directory is not an endorsement.

Effect of Prolonged (72 Hour) Glucagon Administration on Energy Expenditure in Healthy Obese Subjects (NCT03139305) · Clinical Trials Directory