NCT03137472

TMS for Complex Regional Pain Syndrome

Transcranial Magnetic Stimulation (TMS) for Complex Regional Pain Syndrome (CRPS)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The aim of the current study is to assess the efficacy of TMS in the treatment of Complex Regional Pain Syndrome (CRPS). It is hypothesized that participants who receive TMS (Group 1) relative to sham treatment (Group 2) once daily for two days will demonstrate a greater improvement in CRPS-related pain and other associated symptomology (i.e., cognitive, emotional and physical) compared to baseline. Participants will be followed until they reach their baseline for two consecutive weeks to assess safety and duration of symptom alleviation.

Conditions

• Complex Regional Pain Syndromes

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation (TMS)	The Magventure TMS stimulator will be used to perform intermittent theta burst followed by high frequency Transcranial Magnetic Stimulation (TMS).

Timeline

• Start date: 2017-04-24
• Primary completion: 2026-06-29
• Completion: 2026-06-29
• First posted: 2017-05-02
• Last updated: 2025-05-13

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study