NCT03136042

Sputum Induction by Physiotherapy and Hypertonic Saline Techniques in Asthmatic Children

A Randomized Crossover Study of Sputum Induction by Physiotherapy and Hypertonic Saline Techniques in Asthmatic Children.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: University of Sao Paulo · Academic / Other
• Sex: All
• Age: 7 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

This study evaluated whether physiotherapy is efficient in sputum induction and in evaluation of pulmonary inflammation in asthmatic children.

Detailed description

The hypertonic saline is a traditional technique to collect induced sputum, it´s safe and viable in asthmatic children, as well as the technique of sputum induction and processing has been standardized for schoolchildren. Sometimes researchers have difficulties to obtain induced sputum in stable patients and it´s possible to use physiotherapy maneuvers to induced sputum. The manouvers are safe for adult and children asthmatics stable. This study aimed to evaluate the effectiveness to collect induced sputum by physiotherapy maneuvers.

Conditions

• Asthma

Interventions

Type	Name	Description
OTHER	physiotherapy techniques	oscillating positive expiratory pressure during nonstop 5 minutes. After that more five minutes to a forced expiratory technique
OTHER	hypertonic saline 3%	four nebulizations with 3% hypertonic saline, the aerosol was generated by an ultrasonic nebulizer
OTHER	saline + physiotherapy maneuvers	sputum induction by hypertonic saline at 3% for seven minutes. And more five minutes under physiotherapists maneuvers

Timeline

• Start date: 2016-01-15
• Primary completion: 2017-08-31
• Completion: 2018-07-05
• First posted: 2017-05-02
• Last updated: 2019-04-17

Locations

1 site across 1 country: Brazil