NCT03134651

Preoperative Anxiety at Oocyte Retrieval

The Effect of Preoperative Anxiety With Depth of Anesthesia During Oocyte Retrieval on IVF Success

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 131 (actual)
• Sponsor: Trakya University · Academic / Other
• Sex: Female
• Age: 25 Years – 43 Years
• Healthy volunteers: Accepted

Summary

This study evaluated the effects of preoperative anxiety and dosage of anesthesia on IVF success. Half of participants according to the recorded Beck's Anxiety Inventory (BAI) score: a low-anxiety group, while the other half high-anxiety group.

Detailed description

Anxiety is common among women hospitalized for oocyte retrieval. Infertility is usually accompanied by psychological and behavioral changes and can result in preoperative anxiety. Sometimes, preoperative anxiety can be serious. Furthermore, in the absence of premedication for oocyte retrieval, severe degrees of anxiety may occur. Anxiety effects the total consumption of analgesic and anesthetic drugs intraoperatively and has a negative impact on recovery from anesthesia. In addition, the negative effect of anesthetic agents used on fertilization and embryo quality during in vitro fertilization (IVF) has been discussed. However, the impact of any of them on fertilization and embryo quality has not been clearly determined to date. Studies have reported different results regarding the negative effects of anesthetic agents on embryo development and fertilization.

Conditions

• Infertility, Female
• Anesthesia Awareness
• Anxiety State

Interventions

Type	Name	Description
DEVICE	Monitoring brain function
DRUG	propofol

Timeline

• Start date: 2014-07-24
• Primary completion: 2016-07-24
• Completion: 2016-09-24
• First posted: 2017-05-01
• Last updated: 2017-05-01