Trials / Active Not Recruiting
Active Not RecruitingNCT03133650
A Trial of a New Type of Photodynamic Therapy (VTP) in the Treatment of Patients With Cancer of the Esophagus Who Have Trouble Swallowing
A Phase I Trial of Vascular-Targeted Photodynamic Therapy in Esophagogastric Cancer Patients With Moderate to Severe Dysphagia
- Status
- Active Not Recruiting
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to establish the highest dose of laser light for WST-11 VTP to treat obstruction from esophageal cancer that can be safely given.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | WST 11-mediated VTP therapy | Administration of WST11 in conjunction with endoscopic illumination at 753 nm emitted by a diode laser and administered to the participant by optical fibre catheters (cylindrical light diffusers) and a standard upper GI endoscope. |
Timeline
- Start date
- 2017-04-26
- Primary completion
- 2027-02-23
- Completion
- 2027-02-23
- First posted
- 2017-04-28
- Last updated
- 2026-04-16
Locations
3 sites across 2 countries: United States, Israel
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03133650. Inclusion in this directory is not an endorsement.