NCT03130153

Topical Analgesic Versus Saline Mouth Rinses in Post Extraction Healing

Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing Among Hypertensive and Non-Hypertensive Patients

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Aga Khan University · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

There is no evidence based guidelines on using saline rinses for post extraction oral care among hypertensives. Similarly, benefit of orally dissolved topical analgesics in addition to orally administered analgesic is questionable.

Detailed description

Objective: To compare the post dental extraction healing among subjects who took simple analgesic tablets dissolved in water versus those who used saline rinses post operatively. Methods: A study will be done among patients who underwent dental extractions at AKHSP dental clinic, Karachi, Pakistan. Carious, periodontally mobile, traumatized or broken down teeth among 20-70 years old in either gender will be included. In addition to the routine prescription of antibiotics and oral analgesics, the hypertensive subjects (n=20) will be advised to take dissolved Aspirin tablet as an oral care while non-hypertensive will be divided into two sub groups (n=20 each), advised saline mouth rinses or dissolved Aspirin for 5 days, respectively. The outcome (healing of the extraction socket) will be evaluated 7 days from the day of extraction on an ordinal scale.

Conditions

• Tooth Extraction Site Healing

Interventions

Type	Name	Description
DRUG	Aspirin Powder	Aspirin powder to be dissolved in water and to be used as mouthwash twice daily for 7 days after tooth extraction.
DRUG	Normal saline	Normal saline to be used as mouthwash twice daily for 7 days after tooth extraction among non-hypertensive subjects.

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-07-15
• Completion: 2017-12-31
• First posted: 2017-04-26
• Last updated: 2018-06-28

Locations

1 site across 1 country: Pakistan