Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT03129074

Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer

A Phase 2, Single Arm Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer as First-line Systemic Therapy

Status
Withdrawn
Phase
Phase 2
Study type
Interventional
Enrollment
0 (actual)
Sponsor
ASLAN Pharmaceuticals · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to assess the efficacy of varlitinib in combination with capecitabine as measured by objective response rate (ORR) assessed by independent central review (ICR), based on RECIST v1.1 criteria.

Detailed description

Also to explore the role of biomarkers as predictors of response and clinical benefit with varlitinib

Conditions

Interventions

TypeNameDescription
DRUGVarlitinibeveryday
DRUGCapecitabinefrom Day 1 to Day 14 followed by 7-day of rest period, every 21 days.

Timeline

Start date
2018-05-01
Primary completion
2020-03-01
Completion
2020-09-01
First posted
2017-04-26
Last updated
2018-05-23

Source: ClinicalTrials.gov record NCT03129074. Inclusion in this directory is not an endorsement.

Study of Varlitinib Plus Capecitabine in Patients With Advanced or Metastatic Biliary Tract Cancer (NCT03129074) · Clinical Trials Directory