Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT03128489

Evaluation of Immunogenicity and Safety of DTPa-IPV/Hib Conjugate Vaccine (Infanrix™-IPV/Hib) Administered at 6, 10 and 14 Weeks in Healthy Indian Infants

Immunogenicity and Safety of GSK Biologicals' DTPa-IPV/Hib Conjugate Vaccine (Infanrix™-IPV/Hib) (SB213503) in Healthy Indian Infants

Status
Withdrawn
Phase
Phase 3
Study type
Interventional
Enrollment
0 (actual)
Sponsor
GlaxoSmithKline · Industry
Sex
All
Age
6 Weeks – 9 Weeks
Healthy volunteers
Accepted

Summary

The purpose of this study is to assess the immunogenicity and safety of DTPa-IPV/Hib when administered at 6, 10 and 14 weeks to healthy Indian infants, as per guidance from the Indian regulatory authority. The 6, 10 and 14 week schedule reflects the current Indian standard of care.

Detailed description

* Experimental design: Phase III, open-label, non-randomised, multi-centric, single-country study with a single group. * Duration of the study: The intended duration of the study will be approximately 3 months per subject. * Treatment group and vaccination schedule: All subjects will receive three doses of the vaccine at 6, 10 and 14 weeks of age. * DTPa-IPV/Hib Group: Subjects who will receive DTPa-IPV/Hib vaccine (Infanrix-IPV/Hib). Other routine registered childhood vaccinations as part of National Immunisation Programme are permitted. Information regarding vaccine administered since birth until study completion will be collected and documented.

Conditions

Interventions

TypeNameDescription
BIOLOGICALInfanrix-IPV/HibSubjects will receive (Infanrix-IPV/Hib) as three-dose primary vaccination course at 6, 10 and 14 weeks of age. The vaccine will be administered intramuscularly, at a 90-degree angle into the anterolateral side of the thigh on the right side. The vaccine should not be administered in the buttock.

Timeline

Start date
2017-12-01
Primary completion
2018-08-01
Completion
2018-08-01
First posted
2017-04-25
Last updated
2017-12-26

Source: ClinicalTrials.gov record NCT03128489. Inclusion in this directory is not an endorsement.