NCT03128242

Oxytocin's Effect on Attention Training

An Eye-tracking Study to Investigate Oxytocin's Effect on Attentional Bias Training

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: Male
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

This study aims to investigate oxytocin's effect on attentional bias training. Healthy participants will undergo a dot-probe task-based training to direct their attention away from negative stimuli (as compared to neutral). Effects of the training will be assessed using an eye-tracking anti-saccade task.

Detailed description

In this study, a dot-probe task will be used to examine if subjects show an attentional bias towards negative stimuli and whether the bias can be modified using a subsequent attentional bias training. During this training participants learn to direct their attention away from threatening stimuli. In a between-subject placebo controlled design participants will receive either intranasal oxytocin or placebo before the training to examine whether oxytocin could facilitate the effects of the attention training. Effects of the training and of oxytocin on the training will be assessed by means of an eye-tracking anti-saccade task. Based on previous studies showing the strongest effects of threat-attentional bias training in high anxious subjects, the study will recruit participants with an elevated trait anxiety.

Conditions

• Healthy

Interventions

Type	Name	Description
DRUG	Oxytocin	intranasal administration of oxytocin (24IU)
DRUG	placebo	intranasal administration of placebo (24IU)

Timeline

• Start date: 2016-11-25
• Primary completion: 2018-12-30
• Completion: 2018-12-30
• First posted: 2017-04-25
• Last updated: 2018-10-29

Locations

1 site across 1 country: China