NCT03124030

Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy

Evaluation of the Intra- and Post- Operative Bleeding After Simple Dental Extraction in Direct Oral Anticoagulant Therapy Patients: a Longitudinal Observational Cohort Study

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 128 (estimated)
• Sponsor: University of Trieste · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

Direct Oral Anticoagulants were recently approved for medical treatment of several condition such as, non valvular atrial fibrillation, deep venous thrombosis, and others, substituting sometimes the conventional oral anticoagulants. The aim of the present study is to observe the possible difference in intra-operative and post-operative bleeding events for single dental extraction.

Detailed description

Many protocols of drug suspension for surgical procedure has been designed, since the introduction of anticoagulant or antiplatelet medications. Nowadays it is not certain if suspension could give more costs than benefits for the surgical procedure itself. With the recent development of the Direct Oral Anticoagulant it is still unclear whether these medications might bring more bleeding events in the intra-operative and post-operative phase after oral surgery procedure, equal to, or more than Oral Anticoagulant Therapy. The purpose of this study is to assess the degree of intra- and post-operative bleeding complication between direct oral anticoagulant therapy patients and Oral Anticoagulant Therapy patients.

Conditions

• Anticoagulant-induced Bleeding
• Dental Diseases

Interventions

Type	Name	Description
PROCEDURE	simple dental extraction	dental extraction is performed by an expert oral surgeon within 20 minutes. Non-resorbable suture are applied

Timeline

• Start date: 2016-08-02
• Primary completion: 2017-11-15
• Completion: 2018-11-15
• First posted: 2017-04-21
• Last updated: 2017-04-21

Locations

1 site across 1 country: Italy