NCT03117218

Correlation Between Quantitative Analysis of Coronary MRA and FFR

Quantitative Analysis of 3T Whole Heart Coronary Magnetic Resonance Angiogram Improves Detection of Functionally Significant Coronary Artery Disease

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 89 (estimated)
• Sponsor: Seoul National University Bundang Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This study aims to evaluate whether quantitative analysis of coronary MR angiogram would improve the detection of functionally-significant coronary artery stenosis.

Detailed description

Coronary MR angiography is performed with a 3.0-T imager with 32-channel coils. Qunatitative analysis of coronary MR angiogram is evaluated on the basis of the signal intensity (SI) profile along the vessel. Quantitative analysis of coronary MR angiogram (QCMRA) is calculated as \[1 - (SImin/SIref)\] x 100, where SImin is minimal SI and SIref is corresponding reference SI. Diagnostic performance of quantitative analysis of coronary MR angiogram for predicting functional significant coronary stenosis was evaluated by using fractional flow reserve (FFR) as the reference standard.

Conditions

• Coronary Artery Disease
• Magnetic Resonance Angiography
• Fractional Flow Reserve

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Coronary MR angiography	Quantitative analysis of coronary MR angiogram

Timeline

• Start date: 2014-07-01
• Primary completion: 2017-12-31
• Completion: 2018-05-31
• First posted: 2017-04-17
• Last updated: 2017-04-18

Locations

1 site across 1 country: South Korea