NCT03115775

CLA and Vitamin D on Protein Turnover

Randomized Controlled Trial to Evaluate the Independent and Combined Effects of Conjugated Linoleic Acids and Vitamin D on Muscle Protein Turnover in Older Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 65 Years – 85 Years
• Healthy volunteers: Accepted

Summary

To conduct a randomized, double-blind, controlled clinical trial to determine the independent and combined effects of dietary conjugated linoleic acid (CLA) and vitamin D supplementation on anabolic signaling, the expression of growth regulatory factors, and muscle protein turnover in older adults.

Conditions

• Protein

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Conjugated linoleic acid	Intervention will last up to 8 weeks. Subjects will receive conjugated linoleic acid (4000 mg Tonalin FFA 80) daily.
DIETARY_SUPPLEMENT	Vitamin D	Intervention will last up to 8 weeks. Subjects will receive vitamin D3 (2000 IU) daily.
DIETARY_SUPPLEMENT	Conjugated linoleic acid and Vitamin D	Intervention will last up to 8 weeks. Subjects will receive conjugated linoleic acid (4000 mg Tonalin FFA 80) and vitamin D3 (2000 IU) daily.
OTHER	Corn oil (placebo)	Intervention will last up to 8 weeks. Subjects will receive corn oil (4000 mg) daily.

Timeline

• Start date: 2017-05-12
• Primary completion: 2019-08-31
• Completion: 2019-08-31
• First posted: 2017-04-14
• Last updated: 2019-11-21

Locations

1 site across 1 country: United States