Clinical Trials Directory

Trials / No Longer Available

No Longer AvailableNCT03114228

An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML)

An Open-labeled, Multi-Center, Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed FLT3-mutated Acute Myeloid Leukemia (AML) Who Are Eligible for Standard Induction and Consolidation Chemotherapy

Status
No Longer Available
Phase
Study type
Expanded Access
Enrollment
Sponsor
Novartis Pharmaceuticals · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to gather and evaluate additional safety data on the combination of midostaurin and standard of care for adult patients with newly diagnosed Fms-like tyrosine kinase receptor (FLT3) mutated Acute Myeloid Leukemia (AML) who are eligible for standard induction and consolidation chemotherapy and are without satisfactory treatment alternatives prior to the commercial availability\* and reimbursement of midostaurin during the regulatory approval process

Conditions

Interventions

TypeNameDescription
DRUGMidostaurinMidostaurin 50 mg (two 25 mg capsules) twice a day on days 8-21

Timeline

First posted
2017-04-14
Last updated
2019-10-15

Locations

2 sites across 1 country: Canada

Source: ClinicalTrials.gov record NCT03114228. Inclusion in this directory is not an endorsement.

An Expanded Treatment Protocol (ETP) of Midostaurin (PKC412) in Patients 18 Years of Age or Older With Newly-diagnosed F (NCT03114228) · Clinical Trials Directory