Trials / Completed
CompletedNCT03110081
Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 57 (actual)
- Sponsor
- The Cleveland Clinic · Academic / Other
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This study aims to assess if Quadratus Lumborum (QL) blocks are non-inferior to epidural analgesia for pain control and opioid consumption through the third postoperative day in patients having open partial nephrectomy. Patients satisfying all inclusion and exclusion criteria will be randomized in a 1:1 ratio to either epidural catheter or QL catheter.
Detailed description
QL blocks with a single shot and catheters infusions may be an alternative to epidural analgesia. However, the relative efficacy, safety, and cost of the two approaches remain unclear. Epidural analgesia is frequently used as a component of multimodal analgesia for thoracic and abdominal surgery. QL block has been introduced recently as a component of multimodal analgesia for lower thoracic and abdominal surgery. In general, insertion of QL catheter is easier and safer than insertion of epidural catheters. QL catheter management is also less complicated than epidural analgesia (fewer catheter displacements and less hemodynamic compromise) and decreases the level of complexity in postoperative care. Our hypothesis is that the subcostal QL approach with a continuous catheter is non-inferior to epidural analgesia for pain control and opioid consumption in patients having open partial nephrectomy procedure.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Quadratus lumborum block | Quadratus lumborum (QL) block for open partial nephrectomy. |
| PROCEDURE | Epidural analgesia | Epidural analgesia for open partial nephrectomy. |
Timeline
- Start date
- 2018-05-01
- Primary completion
- 2020-09-14
- Completion
- 2020-12-14
- First posted
- 2017-04-12
- Last updated
- 2021-04-29
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03110081. Inclusion in this directory is not an endorsement.