NCT03107975

Effect of Human Amniotic Epithelial Cells on Children With Spastic Cerebral Palsy

Effect of Intrathecal Transplant of Human Amniotic Epithelial Cells on Children With Spastic Cerebral Palsy

• Status: Unknown
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 10 (estimated)
• Sponsor: The Second Affiliated Hospital of Fujian Medical University · Academic / Other
• Sex: All
• Age: 1 Year – 5 Years
• Healthy volunteers: Not accepted

Summary

This study aimed to evaluate the therapeutic potential of human amniotic epithelial cell (hAEC) transplant in the management of children with spastic cerebral palsy.

Detailed description

Cerebral palsy is one of the most common congenital (existing at or before birth) disorders of childhood.Spastic cerebral palsy causes stiffness and movement difficulties.There is no cure for the disease now. This study aimed to evaluate the therapeutic potential of human amniotic epithelial cell (hAEC) transplant in the management of children with spastic cerebral palsy. hAEC will be intrathecal transplanted. Functional status is determined by Gross Motor Function Measure-66 and Fine Motor Function Measure. Spasticity is evaluated by using modified Ashworth scale(MAS).

Conditions

• Spastic Cerebral Palsy

Interventions

Type	Name	Description
BIOLOGICAL	human amniotic epithelial cells	intrathecal injection of human amniotic epithelial cells

Timeline

• Start date: 2017-04-01
• Primary completion: 2017-12-31
• Completion: 2018-12-31
• First posted: 2017-04-11
• Last updated: 2017-04-26

Locations

1 site across 1 country: China