NCT03106116

Efficacy of Enhanced External Counterpulsation on Ventricular Function

A Prospective, Randomized Study of Enhanced External Counterpulsation Therapy on Ventricular Function in Patients With Coronary Heart Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 150 (actual)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the efficacy of Enhanced External Counterpulsation (EECP) therapy on ventricular function in patients with coronary heart disease

Detailed description

Patients with coronary heart disease will be randomized into two groups: standard medical treatment and standard medical treatment plus EECP intervention. Ventricular structure and function will be measured and compared.

Conditions

• Coronary Heart Disease

Interventions

Type	Name	Description
DEVICE	Experimental: Enhanced External Counterpulsation	Enhanced External Counterpulsation (EECP) is a technique for assisting the circulation by decreasing the afterload of the left ventricle and augmenting the diastolic pressure externally by applying a negative pressure to the lower extremities during cardiac systole. EECP therapy has been approved by the United States Food and Drug Administration (FDA) for the treatment of refractory angina and heart failure. Administration of 35-36 hours EECP therapy over a 7 week period, one hour session every working day.
DRUG	Standard medical therapy	Guideline- driven standard medical treatment for 7 weeks

Timeline

• Start date: 2017-03-15
• Primary completion: 2018-12-30
• Completion: 2019-03-30
• First posted: 2017-04-10
• Last updated: 2020-11-02

Locations

1 site across 1 country: China