NCT03105505

The Efficacy of Permethrin 5%, Fusidic Acid 1% and Synthomycine 5% for Demodex - Blepharitis

The Efficacy Of Lyclear (Permethrin 5%) Vs Fusidic Acid1% and Synthomycine 5% for Demodex -Blepharitis Treatment, Prospective-Randomized Trial.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 75 (estimated)
• Sponsor: Barzilai Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study aims to investigate the effect of Permethrin 5% treatment on Signs and symptoms of Demodex-blepharitis in comparison to Synthomycine 5% and Fucithalmic (fusidic acid 1%) .

Detailed description

3 arms study. 75 patient total, 25 patients in each group. Group A (study group) patients will apply facially Permethrin 5% every night for 3 months. Group B patients will apply on the eyelids Fusidic acid 1% every night for 3 months. Group C patients will apply on the eyelids Synthomycine 5% every night for 3 months Follow up Evaluation will be made after one week, one month, two months, three months, 4 months and half a year.

Conditions

• Inflammation of the Eyelids

Interventions

Type	Name	Description
DRUG	Permethrin 5%	Facial skin application once a night for 3 months.
DRUG	Synthomycine 5%	Eye ointment, eyelids and eyelashes application (chloramphenicol), once a night for 3 months.
DRUG	Fusidic Acid 1% M/R Eye Drops	viscous eye drops application once a night for 3 months.

Timeline

• Start date: 2017-04-28
• Primary completion: 2018-09-01
• Completion: 2018-09-01
• First posted: 2017-04-10
• Last updated: 2018-01-30

Locations

1 site across 1 country: Israel