NCT03099863

Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Tract Infection

Cytoscopic Antibiotic Irrigant to Reduce Postoperative Urinary Infection: A Randomized Controlled Study

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 242 (actual)
• Sponsor: MetroHealth Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Postoperative urinary tract infections (UTIs) affect 20-30% of patients undergoing elective gynecologic surgery and have a significant socioeconomic impact and cost. Preoperative antibiotics, sterile operating techniques, postoperative antibiotic and non-antibiotic medical therapies have been utilized to attempt to decrease this rate with little improvement. Utilization of an intraoperative antibiotic cystoscopic irrigant may decrease postoperative UTIs. The investigators have designed a prospective randomized controlled study to evaluate the effectiveness of an antibiotic cystoscopic fluid in preventing postoperative urinary tract infections in women undergoing elective pelvic floor surgery with cystoscopy.

Conditions

• Urinary Tract Infections

Interventions

Type	Name	Description
DRUG	Cystoscopic Fluid containing Neosporin G. U. Irrigant	Normal saline cystoscopic fluid containing Neosporin G. U. Irrigant 1mL/1000mL
PROCEDURE	Cystoscopy	Diagnostic cystoscopy performed during pelvic floor surgery
DRUG	Cystoscopic Fluid/Placebo	Normal saline cystoscopic fluid

Timeline

• Start date: 2016-04-01
• Primary completion: 2020-06-01
• Completion: 2020-06-01
• First posted: 2017-04-04
• Last updated: 2021-12-30
• Results posted: 2021-12-30

Locations

1 site across 1 country: United States