NCT03098875

Heart Rate Variability Under Propofol and Sevoflurane

Spectral Analysis of Heart Rate Variability at BIS 25 and BIS 55 Under Propofol or Sevoflurane

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Hôpital Armand Trousseau · Academic / Other
• Sex: All
• Age: 13 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

Patients were randomized into 2 groups according to the anesthetic, propofol or sevoflurane. Induction and maintenance were standardized, and after the end of surgery, two steady-state recordings were performed at BIS 25 and BIS 55. Bispectral Index and ECG were continuously recorded and cardiac autonomic nervous activity was investigated using spectral analysis of RR Interval variability

Conditions

• General Anesthesia

Interventions

Type	Name	Description
DRUG	Sevoflurane	General anesthesia using sevoflurane as a hypnotic agent
DRUG	Propofol	General anesthesia using propofol as a hypnotic agent
DRUG	Remifentanil	General anesthesia using remifentanil as an analgesic.

Timeline

• Start date: 2009-01-01
• Primary completion: 2009-12-01
• Completion: 2010-09-01
• First posted: 2017-04-04
• Last updated: 2017-04-04

Locations

1 site across 1 country: France