Trials / Completed
CompletedNCT03094247
Feeding Malnourished Children Different Types of Fatty Acids to Promote Neurocognitive Development
Improved Polyunsaturated Ready-to-use Therapeutic Food for Improved Neurocognitive Outcomes in Severe Acute Malnutrition
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 2,897 (actual)
- Sponsor
- Washington University School of Medicine · Academic / Other
- Sex
- All
- Age
- 6 Months – 59 Months
- Healthy volunteers
- Not accepted
Summary
An appropriate balance of omega-6 and omega-3 fatty acids is important for support of neurocognitive development in healthy infants and toddlers. In young children recovering from severe acute malnutrition (SAM), excess omega-6 intake depletes omega-3 fatty acid status. This research will evaluate how novel ready-to-use therapeutic foods (RUTF) with balanced fatty acids improve the metabolic and neurocognitive effects in young children in Malawi recovering from SAM, yielding new knowledge that also has implications for development of well-nourished children.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Amoxicillin | All patients with severe acute malnutrition will receive a course of amoxicillin. |
| DIETARY_SUPPLEMENT | HO-RUTF | HO-RUTF: Milk, perilla oil, palm oil, white sugar, high oleic peanuts |
| DIETARY_SUPPLEMENT | D-HO-RUTF | D-HO-RUTF: DHA, milk, perilla oil, palm oil, white sugar, high oleic peanuts |
| DIETARY_SUPPLEMENT | S-RUTF | S-RUTF: Milk, canola oil, palm oil, white sugar, standard peanuts |
Timeline
- Start date
- 2017-10-02
- Primary completion
- 2021-03-23
- Completion
- 2021-03-23
- First posted
- 2017-03-29
- Last updated
- 2022-07-19
Locations
1 site across 1 country: Malawi
Source: ClinicalTrials.gov record NCT03094247. Inclusion in this directory is not an endorsement.