NCT03090516

Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Alzheimer's Disease

Clinical Study on Improving the Cognitive Function of Patients With Mild to Moderate Alzheimer's Disease by Using Ginkgo Biloba Dispersible Tablets

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 240 (estimated)
• Sponsor: The First Affiliated Hospital with Nanjing Medical University · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

This project explores Ginkgo biloba ester dispersible tablets influence on cognitive function in patients with mild-to-moderate elderly, to observe the effects of different intervention time on cognitive function, for alzheimer's patients in drug rehabilitation treatment provides an effective solution.

Detailed description

The assessment of cognitive scales included Minimum Mental State Examination(MMSE), Alzheimer's Disease Assessment Scale-cognition(ADAS-cog), Neuropsychiatric inventory(NPI), quality of Life of Life in Alzheimer's disease(Qol-ADL), activities of Daily living(ADL), Geriatric Depression scale(GDS).Biochemical test included cholesterol, triglycerides, and low density lipoprotein.

Conditions

• Alzheimer's

Interventions

Type	Name	Description
DRUG	Ginkgo biloba dispersible tablets	Arm C：Ginkgo biloba dispersible tablets，0.15g at a time， three times a day.
DRUG	Donepezil	Arm A：Aricept 5mg/day
DRUG	Ginkgo biloba dispersible tablets and Donepezil	Arm B：Ginkgo biloba dispersible tablets，0.15g at a time， three times a day.Aricept 5mg/day.

Timeline

• Start date: 2016-08-10
• Primary completion: 2020-03-10
• Completion: 2020-03-10
• First posted: 2017-03-24
• Last updated: 2019-08-07

Locations

1 site across 1 country: China