NCT03088735

Transfer Strategy in an Oocyte Donation Programme

Pilot Study of the Best Transfer Strategy in an Oocyte Donation Programme: an Intention to Treat Randomized Controlled Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 134 (actual)
• Sponsor: Fundacion Dexeus · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

It has been previously shown that although the activation of the embryonic genome can begin as early as two days of initiation of the embryonic development (D2), it is expressed on day 3 (D3). Without this activation, the embryo can not continue its development. Therefore, it has been suggested that extended culture to blastocyst stage could be an option to identify and better select embryos that have been able to carry out this activation. The purpose of this study is to compare cumulative pregnancy and live birth rates following transfer of cleavage embryos or blastocysts.

Conditions

• Oocyte Donation
• Infertility, Female
• Embryo Transfer

Interventions

Type	Name	Description
PROCEDURE	Blastocyst-stage embryo transfer strategy	Intra-uterine transfer of blastocist if in cleavage embryo stage the oocyte recipient has a mínimum of 3 availables embryos with at least one of good quality to transfer and also the inta-uterine transfer of cleavage embryo (day 3) when the recipient doesn't have the previous criteria.
PROCEDURE	Cleavage-stage embryo transfer strategy	Inta-uterine transferring of cleavage embryo transfer (day 3 of develpment) in oocyte recipients

Timeline

• Start date: 2017-04-05
• Primary completion: 2019-08-31
• Completion: 2019-08-31
• First posted: 2017-03-23
• Last updated: 2021-06-29

Locations

1 site across 1 country: Spain