NCT03086720

Deproteinization as a Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions

Effect of Sodium Hypochlorite Pre-treatment on the Retention of Restorations for Non-carious Cervical Lesions: A Randomized Controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Federal University of Pelotas · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

This study will verify the effect of the application of a substance (10% sodium hypoclorite -NaOCL) in dentin on noncarious cervical lesions, with the aim of increasing the longevity of the restorations performed in this type of lesion. The hypothesis of the present study is that the application of deproteinization solution after acid etching does not influence the failure rate of the restorations.

Detailed description

The purpose of this study will be to evaluate the failure rates of composite restorations of non-carious cervical lesions (NCCL) performed with or without the pre-treatment with 10% sodium hypochlorite (NaOCl) on etched dentin. A randomized controlled split-mouth and double blind clinical trial will be carried out. Patients with at least two NCCL will be selected. Each patient will be received at least one pair of composite restorations (Filtek Z350/3M ESPE), bonded either with 2 techniques: control (acid etching + placebo solution for 60 seconds + Adper Single Bond 2/3M ESPE) or experimental (acid etching + 10% NaOCl for 60 seconds + Adper Single Bond 2). A calibrated examiner will be evaluated the restorations (baseline, 6-, 12-, 24- and 36-month) using the FDI criteria. The primary outcome is retention of the restoration.

Conditions

• Non-carious Cervical Lesions

Interventions

Type	Name	Description
PROCEDURE	Sodium hypochlorite	Application of 10% sodium hypochlorite (60 seconds) after the etching procedure and before the adhesive system.
PROCEDURE	Water	Treatment of acid etched dentin with sterilized water for 60 s before adhesive system application

Timeline

• Start date: 2012-07-01
• Primary completion: 2018-12-01
• Completion: 2018-12-01
• First posted: 2017-03-22
• Last updated: 2017-03-22

Locations

1 site across 1 country: Brazil