NCT03085680

Curcumin and Function in Older Adults

Does Dietary Supplementation With Curcumin Maintain or Improve Physical and Cognitive Function in Aging Adults at Increased Risk for Disability?

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 17 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 65 Years – 99 Years
• Healthy volunteers: Accepted

Summary

This placebo-controlled RCT tests whether dietary supplementation with curcumin maintains or improves cognitive and physical function in older adults who are at high risk of functional decline due existing (mild) functional impairments and elevated biomarkers of inflammation and explore the association between functional changes and changes in biological indicators of active inflammation.

Conditions

• Older Adults
• Physical Function
• Cognitive Function

Interventions

Type	Name	Description
DRUG	Curcumin	Participants will be given curcumin (1000 mg/day), and will be instructed to consume two 500 mg capsules prior to breakfast every morning with a glass of water. Participants will be instructed to follow this dosing regimen throughout the entire three-month treatment period. Compliance with the dosing regimen will be monitored both through interview and by counting capsules left at monthly clinic visits.
DRUG	microcrystalline cellulose	Participants will be instructed to consume two capsules prior to breakfast every morning with a glass of water. Participants will be instructed to follow this dosing regimen throughout the entire three-month treatment period. Compliance with the dosing regimen will be monitored both through interview and by counting capsules left at monthly clinic visits.

Timeline

• Start date: 2017-08-11
• Primary completion: 2019-10-18
• Completion: 2019-10-18
• First posted: 2017-03-21
• Last updated: 2022-07-26
• Results posted: 2022-02-02

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study