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Active Not RecruitingNCT03083288

Evaluating in Vivo PARP-1 Expression With 18F-FluorThanatrace Positron Emission Tomography (PET/CT) in Breast Cancer

Status
Active Not Recruiting
Phase
Phase 1
Study type
Interventional
Enrollment
30 (estimated)
Sponsor
Abramson Cancer Center at Penn Medicine · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Up to 30 evaluable participants with known or suspected breast cancer (BIRADS 5 by imaging) will undergo FTT PET/CT imaging before primary surgery or neoadjuvant therapy. Patients undergoing neoadjuvant therapy may choose to have a second FTT PET/CT scan after the start of therapy (1 days to 3 weeks). FTT PET/CT uptake will be correlated with pathology measures and treatment response, in subjects undergoing neoadjuvant therapy

Conditions

Interventions

TypeNameDescription
DRUG[18F]FluorThanatrace\[18F\]FluorThanatrace is a radiotracer for PET/CT

Timeline

Start date
2017-02-22
Primary completion
2026-02-22
Completion
2026-02-22
First posted
2017-03-20
Last updated
2025-09-10

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03083288. Inclusion in this directory is not an endorsement.