NCT03083158

Immunity to Hepatitis B Vaccine

Identification of Age-dependent Mechanism of Vaccine-induced Immunity to a Single Dose of Hepatitis B Vaccine Using a Systems Biology Approach - a Demonstration Project

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 40 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Infection and cancer is a major cause of death and morbidity, and may be preventable through vaccination. It is not fully understood at the molecular level why some people respond better than others to vaccines until now the technology to assess this has not been available. This has impaired vaccine development. The overall goal of the Human Vaccines Project is to understand the 'rules' of how vaccines work. In this demonstration project the investigators will vaccinate healthy adults with hepatitis B vaccine to start to understand better how it works, ultimately helping with rational vaccine design in the future.

Conditions

• Hepatitis B
• Immunization; Infection

Interventions

Type	Name	Description
DRUG	Hepatitis B vaccine	1.0 ml (20 micrograms) suspension of hepatitis B surface antigen for intramuscular injection

Timeline

• Start date: 2017-03-06
• Primary completion: 2018-02-01
• Completion: 2018-02-01
• First posted: 2017-03-17
• Last updated: 2020-11-25

Locations

1 site across 1 country: Canada