NCT03082950

HPV Infections, Cancer of the Vulva and Therapeutical Success

Influence of Hpv Infections on Therapeutical Outcome of Patients Suffering From Vulvar Cancer and Ist Preinvasive Lesions

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: University of Luebeck · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Not accepted

Summary

HPV infections may be responsible for different types of cancer in females. Primary Goal of the study was to identify the prevalence of an hpv affiliation in retrospective-prospective analysed cohort of patients who suffer from vulvar cancer and their preinvasive lesions.

Detailed description

HPV infections may be responsible for different types of cancer in females. Primary Goal of the study was to identify the prevalence of an hpv affiliation in retrospective-prospective analysed cohort of patients who suffer from vulvar cancer and their preinvasive lesions. After having retrospectively identified patients with vulvar cancer incl. their preinvasive lesions in the clinical registry the hpv status of the samples is prospectively analyzed using a new multiplex pcr Array. Two Groups are build: patients with hpv associated vulvar cancer and patients with non-hpv associated vulvar cancer. Then, the rate of patients who respond to radiotherapy within the Groups is analyzed by building Kaplan meier plots according to the patients survival and recurrence rate.

Conditions

• HPV
• Human Papilloma Virus

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	polymerase chain reaction	PCR is performed with all patients. The result (hpv positive or negative) will define the patiens Group Affiliation.

Timeline

• Start date: 2015-10-01
• Primary completion: 2017-12-01
• Completion: 2018-05-01
• First posted: 2017-03-17
• Last updated: 2018-05-03

Locations

1 site across 1 country: Germany