NCT03081585

Food Reward Processing in the Human Brain

Integration of Homeostatic Signaling and Food Reward Processing in the Human Brain

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 23 (actual)
• Sponsor: University of Heidelberg Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to investigate the influence of different metabolic states and hormonal satiety signalling on responses in neural reward networks.

Detailed description

Given the rapid development of obesity world-wide, a better understanding of the interaction between the encoding of food reward in mesocorticolimbic reward pathways and homeostatic energy regulation is of paramount importance for the development of new treatment strategies. Healthy participants will undergo functional magnetic resonance imaging while performing a task distinguishing between the anticipation and the receipt of either food or monetary reward. Every participant will be scanned twice in a counterbalanced fashion, both during a state of hunger (after 24-hours fasting) and satiety. Blood samples will be collected to assess hormonal satiety signalling. We hope to provide new insights into the neurobiological underpinnings of motivational processing and hedonic evaluation of food reward.

Conditions

• Healthy

Interventions

Type	Name	Description
BEHAVIORAL	Satiety State	Participants were scanned twice: once after a meal and once after fasting for 24 hours

Timeline

• Start date: 2015-06-09
• Primary completion: 2016-06-10
• Completion: 2016-06-10
• First posted: 2017-03-16
• Last updated: 2022-03-29