Clinical Trials Directory

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UnknownNCT03080519

Endovascular Therapy for Renal Artery Stenosis in China

A Multicenter Registry of Endovascular Therapy for Renal Artery Stenosis in China

Status
Unknown
Phase
N/A
Study type
Interventional
Enrollment
5,000 (estimated)
Sponsor
Chinese Academy of Medical Sciences, Fuwai Hospital · Academic / Other
Sex
All
Age
14 Years
Healthy volunteers
Not accepted

Summary

A multicenter prospective registry planned to recruit more than 5 000 patients with renal artery stenosis was carried out in China. This primary purpose of this study was to evaluate the safety and efficacy of renal artery revascularization in the real world. The secondary purpose was to investigate the etiologic distribution of renal artery stenosis and optimize the indications for renal artery revascularization.

Detailed description

Currently,the endovascular therapy of renal artery stenosis (especially atherosclerotic) remains in dispute. Some randomized control trials published in recent years (including ASTRAL and CORAL trials) showed the lack of additional benefit for renal artery revascularization compared with sole medical therapy. However,these randomized control trials presented a number of limitations including low numbers of patients and non-stringent inclusion criteria. Given clinical medical practice entering the era of big data, the large-sample real-word studies would be more objective to answer some pending issues of randomized controlled trial.Therefore,a multicenter prospective registry planned to recruit more than 5 000 patients with renal artery stenosis was carried out. This primary purpose of this study was to evaluate the safety and efficacy of renal artery revascularization in the real world. The secondary purpose was to investigate the etiologic distribution of renal artery stenosis and optimize the indications for renal artery revascularization.

Conditions

Interventions

TypeNameDescription
PROCEDUREEndovascular TherapyBalloon angioplasty and stenting for renal artery stenosis

Timeline

Start date
2017-04-01
Primary completion
2022-04-01
Completion
2024-04-01
First posted
2017-03-15
Last updated
2017-03-15

Locations

16 sites across 1 country: China

Source: ClinicalTrials.gov record NCT03080519. Inclusion in this directory is not an endorsement.