NCT03079310

Spinal Cord Stimulation for Gait in Parkinson Disease

Thoracic Dorsal Spinal Cord Stimulation for the Treatment of Gait and Balance Impairments in Parkinson Disease

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (estimated)
• Sponsor: Western University, Canada · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Balance and gait impairment increases the risk of falls and contributes to a reduced quality of life and shorter survival in Parkinson disease (PD) and atypical Parkinsonism patients. In preliminary case studies, electrical epidural spinal cord stimulation (SCS) has been shown to significantly improve gait, postural instability, rigidity, and tremor. Controlled studies for optimizing which stimulation settings produce the best clinical response for mobility and gait, and achieving these results chronically are all significant unmet needs. Using quantitative laboratory and mobile technologies to test a range of stimulation settings, this research study aims to determine which SCS parameters or combination of parameters is best suited to effectively alleviate disabling symptoms experienced by each patient.

Conditions

• Parkinson Disease
• Atypical Parkinsonism

Interventions

Type	Name	Description
DEVICE	Spinal cord stimulation	Range of pulse widths (200-500 microseconds) and frequencies (30-130 Hz) will be assessed for each patient

Timeline

• Start date: 2016-02-01
• Primary completion: 2022-04-01
• Completion: 2022-04-01
• First posted: 2017-03-14
• Last updated: 2020-06-23

Locations

1 site across 1 country: Canada