NCT03076424

The Effect of Nutrient Intake on the Microbiome, Weight, and Glucoregulation (NI-MWG)

Is Weight Change and Glucoregulation Related to Dietary Intake, the Gut Microbiome or the Interaction Between The Two Variables?

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 19 (actual)
• Sponsor: North Dakota State University · Academic / Other
• Sex: Female
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to investigate a persons dietary intake and its effect on the gut microbiome and the association of those two variables on weight and glucoregulation. Specifically, the investigators will compare the gut microbiota, fasting glucose and insulin, c-peptide and hemoglobin A1-c in three groups of subjects: obese patients (BMI ≥ 30 kg/m2) with type 2 diabetes mellitus (T2DM), obese patients without T2DM, and normal weight lean controls without T2DM. Each patient will also complete a detailed dietary recall (ASA-24) to investigate the association with diet, microbiome and weight/glucoregulation.

Conditions

• Obesity
• Type2 Diabetes

Interventions

Type	Name	Description
OTHER	no intervention used	Patients will be giving a blood sample after 8 hours of fasting.

Timeline

• Start date: 2017-03-08
• Primary completion: 2017-12-31
• Completion: 2017-12-31
• First posted: 2017-03-10
• Last updated: 2018-08-23

Locations

1 site across 1 country: United States