NCT03075358

Effects of Lidocaine Spray for Reducing Pain During Endometrial Aspiration Biopsy : a Randomized Controlled Trial

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 240 (actual)
• Sponsor: Chiang Mai University · Academic / Other
• Sex: Female
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

Endometrial aspiration biopsy has been accepted as a diagnostic procedure of choice for women with abnormal uterine bleeding to examine endometrial pathology. The procedure has high accuracy comparing to conventional fractional curettage. However, it is associated with significant pain during the procedure. In general, there is no specific recommendation regarding the proper anesthesia used during the procedure. The aim of this study is to examine the effect of lidocaine spray for reducing pain during the endometrial aspiration procedure by comparing it with placebo and no intervention.

Conditions

• Uterine Bleeding

Interventions

Type	Name	Description
DRUG	Lidocaine spray	Patients are locally anesthetized with 8 puffs (80 mg, 10mg/puff, 0.8 ml) of 10% lidocaine spray applied thoroughly to the cervix, 3 minutes before starting the procedure.
OTHER	Normal saline spray	0.8 ml of normal saline spray is applied to the cervix, 3 minutes before starting the procedure

Timeline

• Start date: 2017-03-06
• Primary completion: 2018-01-15
• Completion: 2018-01-15
• First posted: 2017-03-09
• Last updated: 2018-03-27

Locations

1 site across 1 country: Thailand