NCT03074409

The Modulatory Effect of Oxytocin on Interoception

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 83 (actual)
• Sponsor: University of Electronic Science and Technology of China · Academic / Other
• Sex: Male
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This study is designed to investigate oxytocin's effects on interoception and whether these effects vary as a function of different emotional valence.

Detailed description

The present study will use a double-blind, between-subject, placebo-controlled design to investigate the modulatory effect of oxytocin on interoception and whether this effect will vary as a function of emotional valence. In Experiment 1, subjects will perform a heartbeat detection task and the group differences between oxytocin and placebo groups of the interoceptive accuracy and neural activity in the core interoceptive network will be investigated. In Experiment 2, subjects will be asked to watch emotional faces while perform the heartbeat detection task. Investigators will examine whether oxytocin's effects on interoception will be varied as a function of different emotional valence.

Conditions

• Interoception

Interventions

Type	Name	Description
DRUG	oxytocin	self-administration of oxytocin (nasal spray)
DRUG	placebo	self-administration of placebo (nasal spray)

Timeline

• Start date: 2017-03-02
• Primary completion: 2017-09-06
• Completion: 2017-09-12
• First posted: 2017-03-08
• Last updated: 2019-10-18
• Results posted: 2019-10-18

Locations

1 site across 1 country: China