Trials / Unknown
UnknownNCT03072498
Collection of Samples From Patients With MDS
Collection of Bone Marrow, Peripheral Blood (PB), Epithelial Tissue, and Saliva Samples From Patients With Myelodysplastic Syndromes (MDS) to Identify MDS-Specific Antigens (MSA) for Use in Cellular Immunotherapy.
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 24 (estimated)
- Sponsor
- PersImmune, Inc · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to collect information and bone marrow, blood, saliva, cheek cells and skin to be used in the laboratory to assist the sponsor in identifying a new way of treating MDS.
Detailed description
Goals of the study: The purpose of this study is to collect the blood and marrow samples, and non-involved fibroblasts, that are required to identify the unique, personalized array of mutation-driven neoantigens that are expressed by the subject's MDS cells and to assess the feasibility of immunizing and expanding one or more of the patient's T cells ex vivo for investigation of their use as adoptive cellular immunotherapy.
Conditions
Timeline
- Start date
- 2017-04-06
- Primary completion
- 2020-12-05
- Completion
- 2021-03-05
- First posted
- 2017-03-07
- Last updated
- 2019-03-26
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT03072498. Inclusion in this directory is not an endorsement.