NCT03072082

Curative Effect Evaluation of Danlou Tablet on Coronary Artery Disease Not Amenable to Revascularization

Study of Curative Effect Evaluation of DanLou Tablet on Coronary Artery Disease Not Amenable to Revascularization on the Basis of Western Medicine Therapy

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 440 (estimated)
• Sponsor: Jun Li · Academic / Other
• Sex: All
• Age: 45 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether Danlou Tablet is effective in the treatment of coronary artery disease not amenable to revascularization on the basis of western medicine therapy.

Detailed description

The western medicine treatment for CAD not amenable to revascularization is limited. Danlou Tablet, a kind of Chinese patent medicine has been used for treating coronary artery disease in clinical practice in China for many years. Danlou Tablet is applicable to "phlegm-stasis syndrome" in Traditional Chinese Medicine. According to recent studies, Danlou Tablet can reduce blood lipid level and myocardial necrosis area ,promote infarct healing in rats.And it can improve clinical symptoms of patients with CAD.

Conditions

• Coronary Artery Disease(CAD)

Interventions

Type	Name	Description
DRUG	Danlou Tablet	Conventional western medicine \& Danlou Tablet
DRUG	DanLou Tablet placebo	Conventional western medicine \& placebo (for Danlou Tablet)
DRUG	Aspirin Enteric-coated Tablets	100 mg tablet, one tablet daily.
DRUG	Clopidogrel Hydrogen Sulfate 75 MG Oral Tablet	One tablet daily. (for patients who can't use aspirin)
DRUG	Atorvastatin calcium	10 mg tablet, two tablets each night.
DRUG	Isosorbide Mononitrate Tab 20 MG	One tablet two times daily.
DRUG	Metoprolol Tartrate Tab 25 MG	12.5 mg or 25 mg two times daily.
DRUG	Trimetazidine Dihydrochloride Tablets	20 mg tablet, one tablet three times daily.

Timeline

• Start date: 2017-06-01
• Primary completion: 2018-12-01
• Completion: 2019-02-01
• First posted: 2017-03-07
• Last updated: 2017-04-04